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Characterization of a Novel Gene, srpA, Conferring Resistance to Streptogramin A, Pleuromutilins, and Lincosamides in Streptococcus suis Article

Chaoyang Zhang, Lu Liu, Peng Zhang, Jingpo Cui, Xiaoxia Qin, Lichao Ma, Kun Han, Zhanhui Wang, Shaolin Wang, Shuangyang Ding, Zhangqi Shen

Engineering 2022, Volume 9, Issue 2,   Pages 85-94 doi: 10.1016/j.eng.2020.12.015

Abstract: In this study, we identified a new adenosine triphosphate (ATP)-binding cassete (ABC)-F family determinantSrpA shares the highest amino acid identity with Vga(E) (36%) and shows canonical characteristics of ABC-Ffamily members.

Keywords： SrpA     Streptococcus suis     Antibiotic resistance     Ribosome     ABC-F family proteins    

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A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 458-475 doi: 10.1007/s11684-022-0968-4

Abstract: The Ly-6 and uPAR (LU) domain-containing proteins represent a large family of cell-surface markers.based on a systematic survey and comparative genomic study of mouse and human LU domain-containing proteins

Keywords： LU domain-containing protein family     novel human gene     LY6A     pituitary tumor     biomarker     nonsynonymous    

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energy at hydrothermal power plants by simultaneous minimization of pollution and costs using improved ABC

Homayoun EBRAHIMIAN,Bahman TAHERI,Nasser YOUSEFI

Frontiers in Energy 2015, Volume 9, Issue 4,   Pages 426-432 doi: 10.1007/s11708-015-0376-4

Abstract: minimization of hydrothermal units to reach the best solution by employing an improved artificial bee colony (ABC

Keywords： practical constraints of units     pollution function     inlet steam valve     up-ramp rate of units     improved ABC    

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Novel engineered proteins for mechanomaterials

Giuseppe Portale

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 6,   Pages 1122-1123 doi: 10.1007/s11705-020-1941-x

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Epidemiological study of a von Hippel-Lindau family in northwest China

Jingyao Zhang, Dapeng Wu, Hong Ai, Jigang Bai, Shunbin Dong, Qinling Yang, Kai Qu, Lei Zhou, Xinsen Xu, Chang Liu

Frontiers of Medicine 2013, Volume 7, Issue 3,   Pages 378-385 doi: 10.1007/s11684-013-0276-0

Abstract: We encountered a large VHL family in northwest China and conducted a systematic screening of the familyFor the preliminary family screening, physical examination and abdomen B ultrasonography were performedA total of 63 lineal descendants in six generations were observed in the family (generations O, A, B,Therefore, follow-up checkups of the family should be focused on younger generations.Proper family screening protocols should be followed for the treatment of patients with VHL disease.

Keywords： von Hippel-Lindau disease     epidemiology     family screening     pancreatic endocrine tumor    

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Paradoxical role of Id proteins in regulating tumorigenic potential of lymphoid cells

Sumedha Roy, Yuan Zhuang

Frontiers of Medicine 2018, Volume 12, Issue 4,   Pages 374-386 doi: 10.1007/s11684-018-0652-x

Abstract:

A family of transcription factors known as Id proteins, or inhibitor of DNA binding and differentiationDue to their ability to promote self-renewal, Id proteins have been considered as oncogenes, and potentialwith respect to inhibition of their canonical DNA binding partners known as E proteins.Transcriptional regulation by E proteins, and their antagonism by Id proteins, act as gatekeepers toThese mechanistic insights can allow better appreciation of the context-dependent roles of Id proteins

Keywords： Id proteins     lymphoma     leukemia     T cells     B cells     tumor suppressor     oncogene    

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The Advanced Gun Family——the birth of type 95 (5.8 mm) squad gun family

Duo Yingxian

Strategic Study of CAE 1999, Volume 1, Issue 2,   Pages 57-61

Abstract: So after a short period of cooperated work, a new advanced squad gun family has been developed basedThis guns family were already used to equip the army assigned to Hong Kong in January, 1997 and shall

Keywords： squad gun family     automatic rifle     machine rifle     assault rifle    

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Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Frontiers of Medicine   Pages 1006-1009 doi: 10.1007/s11684-023-1000-3

Abstract: Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Keywords： family craniofacial microsomia     Identification novel mutations    

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Family planning technical services in China

Shang-Chun WU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 285-289 doi: 10.1007/s11684-010-0097-3

Abstract: Family planning is a basic state policy in China.Technical services are the key measures for implementing the family planning policy.appropriate contraceptive methods based on the government’s commitment, China has established countrywide family

Keywords： family planning     contraceptive method     service delivery    

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Caveolin proteins: a molecular insight into disease

Hongli Yin,Tianyi Liu,Ying Zhang,Baofeng Yang

Frontiers of Medicine 2016, Volume 10, Issue 4,   Pages 397-404 doi: 10.1007/s11684-016-0483-6

Abstract: This article focuses on the relationship between caveolin proteins and human diseases and reviews the

Keywords： caveolin     caveolae     microRNA     disease     signaling pathway     heart     tumor    

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Discussion on the view of feeding patterns in new era’s family planning services

Yan Xiaoqing

Strategic Study of CAE 2014, Volume 16, Issue 5,   Pages 24-30

Abstract: analyzes general reference volume，the impact of feeding-related factors as well as grass-roots demand for familyexplores the scientific and standardized service examination and evaluation system，enhances the grassroots family

Keywords： feeding patterns     statistical analysis     family planning services    

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SUPEROXIDE DISMUTASE FAMILY GENES IN WATERMELON AND THEIR RESPONSES TO DIFFERENT ABIOTIC STRESSES

Frontiers of Agricultural Science and Engineering 2021, Volume 8, Issue 4,   Pages 645-658 doi: 10.15302/J-FASE -2020350

Abstract: Genome-wide analysis of the SOD gene family in various plant species has been conductedbut little is known about this gene family in watermelon (Citrullus lanatus).Phylogenetic analysis shows that SOD proteins from various plant species can be classified into five

Keywords： abiotic stress / expression analysis / phylogeny / SOD / superoxide dismutase / watermelon    

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A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 330-338 doi: 10.1007/s11684-022-0933-2

Abstract: Clouston syndrome (OMIM #129500), also known as hidrotic ectodermal dysplasia type 2, is a rare autosomal dominant skin disorder. To date, four mutations in the GJB6 gene, G11R, V37E, A88V, and D50N, have been confirmed to cause this condition. In previous studies, the focus has been mainly on gene sequencing, and there has been a lack of research on clinical manifestations and pathogenesis. To confirm the diagnosis of this pedigree at the molecular level and summarize and analyse the clinical phenotype of patients and to provide a basis for further study of the pathogenesis of the disease, we performed whole-exome and Sanger sequencing on a large Chinese Clouston syndrome pedigree. Detailed clinical examination included histopathology, hair microscopy, and scanning electron microscopy. We found a novel heterozygous missense variant (c.134G>C:p.G45A) for Clouston syndrome. We identified a new clinical phenotype involving all nail needling pain in all patients and found a special honeycomb hole structure in the patients’ hair under scanning electron microscopy. Our data reveal that a novel variant (c.134G>C:p.G45A) plays a likely pathogenic role in this pedigree and highlight that genetic testing is necessary for the diagnosis of Clouston syndrome.

Keywords： Clouston syndrome     whole exome sequencing     GJB6 gene     novel variant     unique phenotype    

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Changes in structure and functional properties of whey proteins induced by high hydrostatic pressure:

Xiaoming LIU, Jia NING, Stephanie CLARK,

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 436-442 doi: 10.1007/s11705-009-0251-0

Abstract: the research conducted to understand the effect of HHP on structure and functional properties of whey proteins

Keywords： -lactoglobulin     processing     functional     alternative technology     environmental    

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Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

Frontiers of Medicine doi: 10.1007/s11684-023-1006-x

Abstract: Here, a Pakistani family with parental consanguinity was presented, characterized with severe intellectual

Keywords： neurodevelopmental disorder     autosomal recessive intellectual disability     consanguinity     spastic paraplegia     hearing loss     TMEM141    

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Title Author Date Type Operation

Characterization of a Novel Gene, srpA, Conferring Resistance to Streptogramin A, Pleuromutilins, and Lincosamides in Streptococcus suis

Chaoyang Zhang, Lu Liu, Peng Zhang, Jingpo Cui, Xiaoxia Qin, Lichao Ma, Kun Han, Zhanhui Wang, Shaolin Wang, Shuangyang Ding, Zhangqi Shen

Journal Article

A systematic survey of LU domain-containing proteins reveals a novel human gene, LY6A, which encodes

Journal Article

energy at hydrothermal power plants by simultaneous minimization of pollution and costs using improved ABC

Homayoun EBRAHIMIAN,Bahman TAHERI,Nasser YOUSEFI

Journal Article

Novel engineered proteins for mechanomaterials

Giuseppe Portale

Journal Article

Epidemiological study of a von Hippel-Lindau family in northwest China

Jingyao Zhang, Dapeng Wu, Hong Ai, Jigang Bai, Shunbin Dong, Qinling Yang, Kai Qu, Lei Zhou, Xinsen Xu, Chang Liu

Journal Article

Paradoxical role of Id proteins in regulating tumorigenic potential of lymphoid cells

Sumedha Roy, Yuan Zhuang

Journal Article

The Advanced Gun Family——the birth of type 95 (5.8 mm) squad gun family

Duo Yingxian

Journal Article

Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic

Journal Article

Family planning technical services in China

Shang-Chun WU

Journal Article

Caveolin proteins: a molecular insight into disease

Hongli Yin,Tianyi Liu,Ying Zhang,Baofeng Yang

Journal Article

Discussion on the view of feeding patterns in new era’s family planning services

Yan Xiaoqing

Journal Article

SUPEROXIDE DISMUTASE FAMILY GENES IN WATERMELON AND THEIR RESPONSES TO DIFFERENT ABIOTIC STRESSES

Journal Article

A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome

Journal Article

Changes in structure and functional properties of whey proteins induced by high hydrostatic pressure:

Xiaoming LIU, Jia NING, Stephanie CLARK,

Journal Article

Panoramic variation analysis of a family with neurodevelopmental disorders caused by biallelic loss-of-function

Journal Article